Imidazole compounds with substituted heteroaryl Derivatives, Preparation Process and use in the Prevention and Treatment of disorders mediated by the receptor mGluR5,Acute and / or chronic Neurological Disorders such as Anxiety and cronic Pain

摘要

The present invention relates to imidazole derivatives of the general formula wherein RSUP1/SUP, RSUP2/SUP, RSUP3 /SUPand RSUP4 /SUPare described hereinbelow. These compounds can be used in the treatment or prevention of mGluR5 receptor mediated disorders. These compounds are useful, interalia, in the treatment or prevention of acute and/or chronic neurological disorders such as psychosis, epilepsy, schizophrenia, Alzheimer's disease, cognitive disorders and memory deficits, as well as chronic and acute pain.