首页> 外国专利> new derivatives of benzo b chromeno - naphthyridin - one of pyrano 2 ', 3' - 7 'quino 2,3-b quinoxalin - one, their preparation process and pharmaceutical compositions containing them

new derivatives of benzo b chromeno - naphthyridin - one of pyrano 2 ', 3' - 7 'quino 2,3-b quinoxalin - one, their preparation process and pharmaceutical compositions containing them

机译:苯并[b]铬诺的新衍生物-萘啶-吡喃并[2',3'-7“喹诺[2,3-b]喹喔啉之一-及其制备方法和含有它们的药物组合物

摘要

New benzo [(b)] X1 and Y1 denote groups selected from hydrogen, halogen, hydroxyl, alkoxy, nitro, cyano, trihaloalkene and nrarb, wherein RA and Rb are defined in the description, R1 denotes hydrogen atom or alkyl, R2 denotes groups selected from hydrogen, alkyl and gold atoms. -NR'-AR'-O'-ta-orNR a-C (O) -TaH -O-C (O) -TaH -O-Ta-NRa Rb-NR "a-Ta-OR" a, -NR "a-Ta-CO2R" a, -NR "aC (O) -Ta-NR'aR'b in which R'a, R'b, R'a and Ta are as defined in the description, „R3, R4 represent a hydrogen atom or an alkyl group,„ A represents a group of formula -CH (R5) -CH (R6) -,-CH = C (R7) -,R7=CH-- (O-CH)Among them, R5, R6, R7 and R8 are defined as isomers in the description, N-oxides, and their salt d'adduct acids or pharmaceutically acceptable bases. medicine
机译:新的苯并[[(b)] X1和Y1表示选自氢,卤素,羟基,烷氧基,硝基,氰基,三卤代烯烃和nrarb的基团,其中RA和Rb在说明书中定义,R1表示氢原子或烷基,R2表示基团选自氢,烷基和金原子。 -NR'-AR'-O'-ta-orNR aC(O)-TaH -OC(O)-TaH -O-Ta-NRa Rb-NR“ a-Ta-OR” a,-NR“ a-Ta -CO2R” a,-NR” aC(O)-Ta-NR'aR'b,其中R'a,R'b,R'a和Ta如说明书中所定义,“ R3,R4代表氢原子“ A代表式-CH(R5)-CH(R6)-,-CH = C(R7)-,R7 = CH-(O-CH)的基团,其中R5,R6, R7和R8在说明书中定义为异构体,N-氧化物及其盐,d'加合物酸或药学上可接受的碱。

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