首页>
外国专利>
PYRIMIDO4,5-DPYRIMIDINE DERIVATIVES WITH ANTICANCER ACTIVITY.
PYRIMIDO4,5-DPYRIMIDINE DERIVATIVES WITH ANTICANCER ACTIVITY.
展开▼
机译:具有抗癌活性的嘧啶并[4,5-D]嘧啶衍生物。
展开▼
页面导航
摘要
著录项
相似文献
摘要
Disclosed are novel pyrimido compounds of the formula (I) wherein R1 to R9 are as defined in the specification, that are selective inhibitors of both KDR an FGFR kinases and are selective against LCK. These compounds and their pharmaceutically acceptable salts are anti-proliferative agents useful in the treatment or control of solid tumors, in particular breast, colon, lung and prostate tumors. Also disclosed are pharmaceutical compositions containing these compounds and the use for 10 treating cancer.
展开▼