synthetic immunogenic for the therapy and prophylaxis of the abuse of drugs and psychoactive substances

摘要

Synthetic immunogen represents conjugate as the natural or artificial protein as a carrier and haptene - narcotic or psychotropic compound taken among the following groups of low-molecular compounds. Conjugate is modified with an immunocompetent polyelectrolyte - polyoxidonium in the ratio, weight %: conjugate : polyoxidonium = 1:(1.5-5.0). Invention can be used for treatment of narcomania, intoxication with different poisons in industry and in homes, in technogenic catastrophe and so on. Synthetic immunogen represents conjugate as the natural or artificial protein (egg albumin or human gamma-globulin, or bacterial toxins) as a carrier and haptene - narcotic or psychotropic compound taken among the following groups of low-molecular compounds: aromatic propaneamines or isoquinolines, or diphenylmethanes, or indoleamines, or derivatives of barbituric acid, or derivatives of substituted piperidines. Conjugate is modified with an immunocompetent polyelectrolyte - polyoxidonium in the ratio, weight %: conjugate : polyoxidonium = 1:(1.5-5.0).