Synthetic immunogen for the therapy and prophylaxis of abuses with narcotics and psychoactive substances

摘要

The invention relates to medicine, in particular immunology, and may in the therapy of narcomania, poisoning with different toxins in industry, in everyday life, in Technogenkatastrophen u. Ä. be exploited. The invention core is that the synthetic immunogen comprises the conjugate in the form of a carrier - the natural or the artificial protein (Eialbinum or human gammaglobulin or micro toxins) and the hapten - of the psychopharmaceutical compound from the next groups of compounds low molecular weight: Aromapropanamine or isoquinolines or diphenylmethanes or indoleamines or derivatives of barbituric acid or derivatives of substituted pyperidines. The conjugate is modified with the immunocompetent polyelectrolyte - polyoxonium - at the ratio of wt%: conjugate: polyoxonium = 1: 1.5-5.0. The advantage of the invention is the high immune activity, the reduction of doses and the shortening of the treatment time.