NEW HYDRONAFTALENIC COMPOUNDS PREPARED THROUGH A RING OPENING REACTION CATALIZED BY RHODIUM IN THE PRESENCE OF A PHOSPHINE BINDING.

摘要

A compound according to formula I: wherein R is - (CH2) nR1 and R1 is a C3-C6 aryl optionally substituted in one or more positions with a group selected from: Cl; F; NO2; I; Br; a C1-C3 alkyl; and a C1-C3 alkoxy; and in which n = 0-3; wherein X and Y are independently selected from the group consisting of H; NH2; F; Cl; Br; a C1-C3 alkyl; and a C1-C3 alkoxy; or in which adjacent X and Y, or Y and Y together with the carbon atoms to which they are attached, form a C3-C6 carbocyclic ring or a C3-C6 heterocyclic ring containing one or more heteroatoms selected from the group consisting of: O; N; and S; and wherein Z is selected from O or NRa, where Ra is selected from: (i) phenyl; (j) (O) C-O-Rb, wherein Rb is a linear or branched C1-C6 alkyl; (k) -SO2-Rc, wherein Rc is selected from the group consisting of: i) linear or branched C1-C6 alkyl; ii) - (CH2) qRe, in which q = O-3 and Re is a C3-C6 aryl, optionally substituted in one or more positions with a group selected from Cl; F; NO2; CN; I; Br; a linear or branched C1-C3 alkyl; a C1-C3 alkoxy; and -C (O) Rf, wherein Rf is a C1-C3 alkyl; - (CH2) rCF3, in which r = 0-3; iii) -Rg (CF3) s, wherein Rg is a linear or branched C1-C3 alkyl, and s = 1-3; iv) - (CH2) s-TMS, in which TMS = trimethylsilyl and s = 1-3; (l) -SO2- (CH2) q-Si (CH3) 3 in which q is 1-3.