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TETRAHYDROQUINOLINE DERIVATIVES FOR THE INHIBITION OF DISEASES ASSOCIATED WITH THE PRIVACY OF STROGENS OR WITH AN OPEN PHYSIOLOGICAL RESPONSE TO ENDOGENOUS STROGENS.
TETRAHYDROQUINOLINE DERIVATIVES FOR THE INHIBITION OF DISEASES ASSOCIATED WITH THE PRIVACY OF STROGENS OR WITH AN OPEN PHYSIOLOGICAL RESPONSE TO ENDOGENOUS STROGENS.
The use of a compound of the formula ** (Formula) ** in which R1 is -H, -OH, -O (C1-C4 alkyl), -OCOC6H5, -OCO (C1-C6 alkyl) or -OSO2 ( C2-C6 alkyl); R2 and R3 are each independently -H, -OH, -O (C1-C4 alkyl) -OCO C6H5, -OCO (C1-C6 alkyl), -OSO2 (C2-C6 alkyl) or halo, R4 is 1 -piperidinyl, 1-pyrrolidinyl, methyl-1-pyrrolidinyl, dimethyl-1-pyrrolidinyl, 4-morpholino, dimethylamino, diethylamino diisopropylamino or 1-hexamethyleneimino; n is 1, 2 or 3; or a pharmaceutically acceptable salt thereof, for the manufacture of a medicament for the inhibition of diseases associated with estrogen deprivation.
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机译：使用式**（式）**的化合物，其中R1为-H，-OH，-O（C1-C4烷基），-OCOC6H5，-OCO（C1-C6烷基）或-OSO2（C2 -C6烷基）; R 2和R 3各自独立地为-H，-OH，-O（C 1 -C 4烷基）-OCO C 6 H 5，-OCO（C 1 -C 6烷基），-OSO 2（C 2 -C 6烷基）或卤素，R 4为1-哌啶基， 1-吡咯烷基，甲基-1-吡咯烷基，二甲基-1-吡咯烷基，4-吗啉代，二甲氨基，二乙氨基二异丙氨基或1-六亚甲基亚氨基; n为1、2或3;或其药学上可接受的盐，用于制造抑制与雌激素剥夺有关的疾病的药物。
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