Polyacrylates and poly (alkyl) acrylates cationic or the corresponding acrylamides for use in synthetic transfection systems.

摘要

The present invention concerns a synthetic transfection or blocking system comprising, as carrier, a polyacrylate cationic water soluble or water dispersible, a polyacrylamide, a poly (C 1-6 alkyl) acrylate, or poly ( C 1-6 alk) acrylamide. Further it relates to a method for introducing DNA fragments in target cells, comprising contacting of these DNA fragments a polyacrylate, polyacrylamide, poly (C 1-6 alkyl) acrylate or poly (C 1-6 alk) acrylamide , which is at least partially substituted with cationic substituents and putting Next, the obtained transfection system with target cells. Finally, the invention involves the use of a polyacrylate, a polyacrylamide, a poly (C 1-6 alkyl) acrylate, or poly (C 1-6 alk) acrylamide, which is at least partially substituted with cationic substituents AS A CARRIER SYSTEM DNA.