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CATIONIC POLYACRYLATES AND POLY(ALKYL)ACRYLATES OR THE CORRESPONDING ACRYLAMIDES FOR USE IN SYNTHETIC TRANSFECTION SYSTEMS
CATIONIC POLYACRYLATES AND POLY(ALKYL)ACRYLATES OR THE CORRESPONDING ACRYLAMIDES FOR USE IN SYNTHETIC TRANSFECTION SYSTEMS
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机译:阳离子聚丙烯酸酯和聚(烷基)丙烯酸酯或相应的丙烯酰胺,用于合成翻译系统
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摘要
The present invention relates to a synthetic transfection or blocking system comprising as a carrier a cationic, water soluble or water dispersable polyacrylate, a polyacrylamide, a poly(C1-6 alkyl)acrylate or poly(C1-6 alkyl)acrylamide. In addition, it relates to a method for introducing DNA fragments in target cells, comprising contacting these DNA fragments with a polyacrylate, a polyacrylamide, a poly(C1-6 alkyl)acrylate or poly(C1-6 alkyl)acrylamide, which is at least partially substituted with cationic substituents and subsequently contacting the obtained transfection system with target cells. Finally, the invention involves the use of a polyacrylate, a polyacrylamide, a poly(C1-6 alkyl)acrylate or poly(C1-6 alkyl)acrylamide, which is at least partially substituted with cationic substituents as a DNA carrier system.
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