METHOD FOR INDUCING HEPATITIS C VIRUS (HCV) REPLICATION IN VITRO, CELLS AND CELL LINES ENABLING ROBUST HCV REPLICATION AND KIT THEREOF

摘要

The present invention relates to hepatitis C virus(HCV). More particularly, the invention relates to the development of atool suitable for the search and validation of novel HCV antiviral drugsand therapies (e.g. vaccine). The invention further relates to methodsfor inducing HCV replication in vitro, and more particularly to a simple invitro replication assay of HCV which enables productive and sustainedinfectious HCV production.