PROCESS FOR PRODUCING PAD BASE FOR TRANSDERMAL DRUG ADMINISTRATION, PAD BASE FOR TRANSDERMAL DRUG ADMINISTRATION AND NEEDLE

摘要

In the conventional micropatch method, the skin is pricked with solid needles,and vibration is applied by means of a vibrator so as to increase the needle-skin interstice to thereby accomplish drug administration. In the invention,there are provided a pad base for transdermal drug administration wherebytransdermal administration of a medicinal drug can be accomplished withoutneed to apply vibration, and provided a process wherein the pad base caneasily be produced. One end of each of metal thin wires is immersed in thevertical direction in a synthetic resin raw material solution so as to causethe synthetic resin raw material solution to adhere to the circumference ofthe metal thin wires. The synthetic resin raw material solution is hardened,and thereafter the metal thin wires are pulled out. Thus, there can beobtained a structure comprising adherent substrate (2) and, disposed erect onthe skin side surface thereof, microneedles (1) being tubular and having bell-bottom outer wall. Medicinal drug charged in the hollow portion (3) ofmicroneedles (1) can be injected in the skin, thereby effecting transdermaldrug administration. Further, the microneedles (1) are resistant to breakingoff because of the bell-bottom shaping.