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Process for producing pad based for transdermal drug administration, pad base for transdermal drug administration and needle

机译:基于透皮给药的垫的生产方法,透皮给药的垫基和针头

摘要

According to a conventional MicroPatch method, a drug is administrated by stinging the skin with a solid-core needle, and broadening a gap between the needle and the skin by vibration with a vibrator. Consequently, the object of the present invention is to provide a pad base for endermism capable of administrating a drug in the skin without vibration, and to provide a production process capable of easily obtaining the pad base. One side end of the thin metal wire is immersed in a solution containing a synthetic resin raw material in a lengthwise direction, the synthetic resin raw material solution adheres to a periphery of the thin metal wire, the synthetic resin raw material solution is hardened and then the thin metal wire is pulled out. There is obtained the minute needle 1 which is installed upright on the skin side of a patch base 2, wherein the minute needle is a hollow tubular body and the outer wall thereof is thickened toward the bottom. A drug in the hollow portion 3 of the minute needle 1 is injected in the skin and can be provided for endermism. Further, since the minute needle 1 spreads and is thickened toward the bottom, it hardly fractures.
机译:根据常规的MicroPatch方法,通过用实心针刺痛皮肤并且通过利用振动器的振动来加宽针头和皮肤之间的间隙来施用药物。发明内容因此,本发明的目的是提供一种能够在没有振动的情况下在皮肤中施用药物的用于雌激素症的垫基,并且提供一种能够容易地获得该垫基的生产方法。将细金属线的一侧端沿长度方向浸入包含合成树脂原料的溶液中,该合成树脂原料溶液粘附至细金属线的周围,使合成树脂原料溶液硬化,然后将细金属线拉出。获得分钟针 1 ,其垂直安装在贴剂基座 2 的皮肤侧,其中,分钟针是空心管状体,其外壁是向底部变厚。将细针 1 的中空部分 3 中的药物注射到皮肤中,并可以用于性病。此外,由于细针 1 展开并向底部变粗,因此几乎不断裂。

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