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METHOD OF JUDGING SENSITIVITY OF CANCER CELL TO Eg5 INHIBITOR

机译:判断癌细胞对Eg5抑制剂敏感性的方法

摘要

A method which comprises measuring the sensitivities to an Eg5 inhibitor of two or more human cancer cell lines and the expression amounts of one or more human genes and identifying a gene showing a correlation between its expression amount and the sensitivity to the Eg5 inhibitor as a gene relating to the sensitivity to the Eg5 inhibitor. A method which comprises selecting one or more genes from the genes relating to the sensitivity to the Eg5 inhibitor thus identified, measuring the expression amounts of the selected genes in cancer cells, assigning scores depending on the expression amounts and thus judging the sensitivity of the cancer cells to the Eg5 inhibitor.
机译:一种方法,其包括测量对两种或更多种人类癌细胞系的Eg5抑制剂的敏感性和一种或多种人类基因的表达量,并鉴定出在其表达量和对Eg5抑制剂的敏感性之间具有相关性的基因作为基因。与对Eg5抑制剂的敏感性有关。一种方法,包括从与由此鉴定出的对Eg5抑制剂的敏感性有关的基因中选择一个或多个基因,测量所选基因在癌细胞中的表达量,根据表达量分配分数,从而判断癌症的敏感性细胞到Eg5抑制剂。

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