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Method for determining sensitivity of cancer cells to Eg5 inhibitor

机译:测定癌细胞对Eg5抑制剂敏感性的方法

摘要

The sensitivity to Eg5 inhibitor and the expression level of at least one human gene are measured for two or more human cancer cell lines, and a gene having a correlation between the expression level and sensitivity to Eg5 inhibitor is determined as an Eg5 inhibitor. To identify as a gene involved in susceptibility to By selecting one or more genes from among the genes involved in sensitivity to the identified Eg5 inhibitor, measuring the expression level of the selected gene in cancer cells, and assigning a score corresponding to the expression level, the cancer A method for determining the sensitivity of a cell to an Eg5 inhibitor.
机译:对两种以上的人类癌细胞系,测定对Eg5抑制剂的敏感性和至少一个人类基因的表达水平,将表达水平与对Eg5抑制剂的敏感性相关的基因确定为Eg5抑制剂。通过将一个或多个基因从对鉴定出的Eg5抑制剂的敏感性中所涉及的基因中选择一个或多个基因,测量所选基因在癌细胞中的表达水平,并分配一个与该表达水平相对应的分数,来确定其为易感性基因。癌症一种确定细胞对Eg5抑制剂敏感性的方法。

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