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A packaging cell line expressing for use in facilitating the development of high capacity adenoviral vectors
A packaging cell line expressing for use in facilitating the development of high capacity adenoviral vectors
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机译:表达用于促进高容量腺病毒载体开发的包装细胞系
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摘要
The present invention relates to gene therapy, especially to adenovirus-based gene therapy, and related cell lines and compositions. In particular, novel packaging cell lines are disclosed, for use in facilitating the development of high-capacity vectors. The invention also discloses a variety of high-capacity adenovirus vectors and related compositions and kits including the disclosed cell lines and vectors. Finally, the invention discloses methods of preparing and using the disclosed vectors, cell lines and kits.
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