首页> 外国专利> COMPOSITION COMPRISING TRITERPENE HAVING IMMUNE REGULATING ACTIVITY FOR PREVENTION AND TREATMENT OF ALLERGIC DISEASE AND IMPROVEMENT OF IMMUNOTHERAPY EFFICACIES

COMPOSITION COMPRISING TRITERPENE HAVING IMMUNE REGULATING ACTIVITY FOR PREVENTION AND TREATMENT OF ALLERGIC DISEASE AND IMPROVEMENT OF IMMUNOTHERAPY EFFICACIES

机译:具有预防和治疗变应性疾病和改善免疫疗法功效的免疫调节活性的包含三苯乙炔的组合物

摘要

PURPOSE: Provided is a composition comprising triterpene based compounds which have immune regulating activity. Therefore, the composition increases the synthesis of IgG2a while inhibiting synthesis of Th2 cytokines, IL-4 and IL-5 and thus prevents and treats allergic diseases and improves immunotherapy efficacies. CONSTITUTION: The pharmaceutical composition for prevention and treatment of allergic diseases and immunotherapy is characterized by containing triterpene based compounds as active ingredients. The triterpene based compounds include adianane, arborene, cucurbitacin, dammarane, eburicane, euphane, fernane, friedelin, hopane, lanostane, lupane, meliacane, oleanane, protostane, serratane and taraxerane.
机译:目的:提供包含具有免疫调节活性的基于三萜的化合物的组合物。因此,该组合物增加了IgG2a的合成,同时抑制了Th2细胞因子,IL-4和IL-5的合成,从而预防和治疗了过敏性疾病并提高了免疫疗法的效率。组成:用于预防和治疗过敏性疾病及免疫疗法的药物组合物,其特征在于含有三萜类化合物作为活性成分。基于三萜烯的化合物包括金刚烷,阿硼烷,葫芦素,达玛烷,延胡索烷,番红花,fernane,friedelin,hop烷,羊毛甾烷,卢潘烷,me烷,齐墩果烷,前炔烷烃,Serratane和taraxerane。

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