EXTRACTION METHOD OF GLYCYRRHIZIC ACID USING SUPERCRITICAL FLUID EXTRACTION

摘要

The present invention is characterized by a method for producing glycyrrhizinic acid comprising extracting crushed licorice with supercritical carbon dioxide, water and cosolvent at a temperature of 40 to 120 ° C., a pressure of 11 to 50 Mpa, and an apparent flow rate of 0.27 to 5.1 cm / min. .;According to the present invention, not only can a high yield of glycyrrhizinic acid be obtained in a short time from the crushed licorice, but also an effect of producing an environmentally friendly glycyrizinic acid using carbon dioxide, a solvent that is harmless to the human body, can be produced. There is.