首页> 外国专利> Composition comprising the extract of Astilbe rubra or Astilbic acid and Peltoboykinolic acid derivatives having anti-inflammatory or anti-allergic activity

Composition comprising the extract of Astilbe rubra or Astilbic acid and Peltoboykinolic acid derivatives having anti-inflammatory or anti-allergic activity

机译:组合物,其包含具有抗炎或抗过敏活性的杨梅或抗坏血酸提取物和枯草果酸衍生物

摘要

The invention deer urine (Astilbe rubra) relates to a composition containing the extract, Astilbe chinensis extract a Oh steel biksan (Astilbic acid, ACH53c) separated from or pelto show kinol acid (Peltoboykinolic acid) having anti-inflammatory and anti-allergic activity by containing derivatives of activated platelets that cause various inflammatory disease factor (PAF, platelet activating factor) precursor resources PAF resources PAF- acetyl aminotransferase claim (lysoPAF-acetyltransferase), an enzyme for synthesizing a PAF from (lysoPAF) of various inflammatory and allergic diseases by the inhibiting activity prevents at the same time has an activity to inhibit the production of PAF, the generation of lipoxygenase (5-LO, 5-lipoxygenase) inflammatory eicosanoids (eicosanoid) to inhibit the activity of the present invention relates to a pharmaceutical composition for preventing and treating.
机译:本发明的鹿尿(Astilbe rubra)涉及一种组合物,该组合物包含一种提取物,即从草皮中分离出的Oh钢Biksa​​n(草酸,ACH53c)提取物,或显示出具有抗氧化作用的木酚酸(Peltoboykinolic acid)。通过包含引起各种炎性疾病因子(PAF,血小板活化因子)的活化血小板的衍生物的炎症和抗过敏活性前体资源PAF资源PAF-乙酰氨基转移酶(lysoPAF-乙酰转移酶),一种由(lysoPAF)合成PAF的酶对各种炎性和变态性疾病的抑制作用均通过抑制活性来防止,同时具有抑制PAF产生的活性,产生脂氧合酶(5-LO,5-脂氧合酶)的炎性类花生酸(eicosanoid)具有抑制活性。本发明涉及用于预防和治疗的药物组合物。

著录项

  • 公开/公告号KR100523462B1

    专利类型

  • 公开/公告日2005-11-09

    原文格式PDF

  • 申请/专利权人

    申请/专利号KR20050052041

  • 申请日2005-06-16

  • 分类号A61K35/78;

  • 国家 KR

  • 入库时间 2022-08-21 22:03:16

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