Releasing different drugs from a stent after implantation comprises releasing an immediate-action drug in a rapid process and releasing a sustained-action drug in a long-term process

摘要

Releasing different drugs from a stent after implantation into a human or animal body comprises releasing an immediate-action drug (D2) in a rapid process and releasing a sustained-action drug (D1) in a long-term process. An independent claim is also included for a stent for implantation into a lumen in a human or animal body, comprising a sustained-action drug (D1) releasably held in a base layer and an immediate-action drug (D2) releasably held in an additional drug layer, where D1 is released over a longer period than D2. ACTIVITY : Vulnerary; Vasotropic; Anticoagulant; Antiinflammatory; Cytostatic; Immunosuppressant. MECHANISM OF ACTION : Integrin Antagonist; Thrombocyte Aggregation Inhibitor; Migration Inhibitor; Prolyl Hydroxylase Inhibitor; Protease C Inhibitor.