首页> 外国专利> New oligonucleotides, useful for treating cancer, especially of the pancreas, are not species specific but induce apoptosis or inhibit proliferation

New oligonucleotides, useful for treating cancer, especially of the pancreas, are not species specific but induce apoptosis or inhibit proliferation

机译:用于治疗癌症(尤其是胰腺癌)的新型寡核苷酸不是物种特异性的,但会诱导凋亡或抑制增殖

摘要

Oligonucleotide (ON) that includes an arrangement of at least 6, preferably 8, consecutive nucleotides (nt) from (S1) is new. Oligonucleotide (ON) that includes an arrangement of at least 6, preferably 8, consecutive nucleotides (nt) from (S1) is new. 5'-CCTGTTGTTTTCTCT-3' (S1) ACTIVITY : Cytostatic. MECHANISM OF ACTION : (I) are non-sequence specific inhibitors of cancer cell proliferation or inducers of apoptosis.
机译:(S1)中包含至少6个,优选8个连续核苷酸(nt)的排列的寡核苷酸(ON)是新的。 (S1)中包含至少6个,优选8个连续核苷酸(nt)的排列的寡核苷酸(ON)是新的。 5'-CCTGTTGTTTTCTCT-3'(S1)活性:细胞稳定。作用机理:(I)是癌细胞增殖的非序列特异性抑制剂或凋亡诱导剂。

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