首页> 外国专利> RECOMBINANT VECTOR FOR DETECTING MUTAGENICITY AND HUMAN CELL AND METHOD FOR DETECTING MUTAGENICITY

RECOMBINANT VECTOR FOR DETECTING MUTAGENICITY AND HUMAN CELL AND METHOD FOR DETECTING MUTAGENICITY

机译:用于检测致突变性和人类细胞的重组矢量和用于检测致突变性的方法

摘要

PPROBLEM TO BE SOLVED: To provide a recombinant vector for detection of mutagenicity for directly detecting mutagenicity of a sample to be detected in a human cell, and the human cell and to provide a method for detecting mutagenicity. PSOLUTION: In the recombinant vector, when the vector itself is mutated by a sample to be examined, a reporter gene is translated so as to function as a reporter and when the vector itself is not mutated by the sample to be examined, a regulatory gene for controlling translation of the reporter gene so that the reporter gene is not translated is inserted into the upstream of the reporter gene. PCOPYRIGHT: (C)2007,JPO&INPIT
机译:解决的问题:提供一种用于检测致突变性的重组载体,以直接检测人细胞中待检测样品的致突变性,并提供一种检测致突变性的方法。

解决方案:在重组载体中,当载体本身被待检样品突变时,报告基因被翻译成具有报道基因的功能,而当载体本身未被待检样品突变时,将用于控制报道基因的翻译以使报道基因不被翻译的调节基因插入到报道基因的上游。

版权:(C)2007,日本特许厅&INPIT

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