MDP DERIVATIVE AND CONJUGATE HAVING HEMATOPOIETIC FUNCTION-STIMULATING ACTIVITY, AND COMPOSITION CONTAINING THE SAME

摘要

PROBLEM TO BE SOLVED: To provide a pharmaceutical composition capable of mobilizing a large amount of stem cells derived from the bone marrow and forming the stem cells in the blood flow by stimulating hematopoietic function.;SOLUTION: The pharmaceutical composition contains at least one of water-soluble muramyl peptide derivatives such as muradimetide, muroctasine and MTP-PE, and is used for stimulating the hematopoietic function, and preventing the bone marrow toxicity effects caused by some kinds of treatments. The pharmaceutical composition is preferably prepared so that 0.1-25 mg dose per kg human body weight can be orally administered.;COPYRIGHT: (C)2006,JPO&NCIPI