AGENT FOR TREATMENT OF DISEASE CAUSED E.G. BY NERVE CELL DEGENERATION AND CONTAINING SALVIANOLIC ACID B, OR THE LIKE

摘要

PROBLEM TO BE SOLVED: To provide a new agent for the treatment of diseases caused by nerve cell degeneration, etc., its active component, a method for the preparation of the active component, and a substance and technique necessary for the method.;SOLUTION: It has been found that a compound selected from salvianolic acid B, its optical or geometrical isomer having an action similar to salvianolic acid B, their prodrugs, pharmacologically permissible salt and hydrate of the above compounds and their prodrugs has an action to effect the proliferation and/or differentiation of a neural stem cell while protecting the neural stem cell or its differentiated cell. The finding induces the development of an agent acting on the neural cell and containing these substances as active components, a method for acting on the neural cell by using the acting agent, a method for the preparation of liquid containing neural cell and produced by using the acting method, a liquid containing neural cell and produced by using the preparation method, and an agent for the treatment of diseases caused e.g. by neural cell degeneration by using the acting agent and/or the liquid containing the neural cell as active components.;COPYRIGHT: (C)2006,JPO&NCIPI