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Methods and products related to the intracellular delivery of polysaccharides

机译:与多糖细胞内递送有关的方法和产品

摘要

The invention relates, in part, to methods and compositions for the intracellular delivery of polysaccharides. In particular, the methods and compositions relate to the intracellular delivery of glycosaminoglycans, such as heparin. The invention in other aspects relates to the use of glycosaminoglycans for the treatment of proliferative disorders, such as cancer. The invention is still other aspects relates to improving cell viability. The invention also relates to the delivery of polysaccharides while avoiding unwanted effects of the polysaccharides. For example, heparin can be delivered while avoiding its anticoagulant effects.
机译:本发明部分地涉及用于细胞内递送多糖的方法和组合物。特别地,所述方法和组合物涉及糖胺聚糖例如肝素的细胞内递送。本发明在其他方面涉及糖胺聚糖在治疗增生性疾病例如癌症中的用途。本发明的其他方面涉及提高细胞生存力。本发明还涉及多糖的递送,同时避免了多糖的有害作用。例如,肝素可以在递送的同时避免其抗凝作用。

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