Degradation inhibitor for hepatitis b virus x interacting protein

摘要

It was discovered that hepatitis B virus x interacting protein (XIP) is cleaved and degraded by caspase-1, and the cleavage recognition site of XIP was also discovered. Based on these findings, the present invention provides a method and composition for inhibiting the degradation of XIP, more particularly, inhibiting the degradation of XIP caused by caspase-1, preventing and/or treating a disease attributable to the degradation of XIP, inhibiting the replication and/or transcription of hepatitis B virus, preventing and/or treating hepatitis B, and preventing and/or treating hepatic cancer caused by hepatitis B virus.