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Microstructures for delivering a composition cutaneously to skin

机译:用于将组合物经皮肤递送至皮肤的微结构

摘要

An improved method and apparatus is provided as a system to deliver a composition, preferably a medical or pharmaceutical composition or active, through the stratum corneum of skin, without introducing bleeding or damage to tissue, and absent pain or other trauma. The dimensions and shapes of the microelements are controlled so as to control the penetration depth into the skin. The microelements can be “hollow” such that passageways are created therethrough to allow the composition to flow from a chamber, through the microelements, and into the skin. Alternatively, the microelements can be “solid,” and the composition is applied directly to the skin just before or just after the microelements are applied to the skin surface to create the openings in the stratum corneum.
机译:提供了一种改进的方法和设备作为系统,其通过皮肤角质层递送组合物,优选医学或药物组合物或活性物,而不会引起出血或组织损伤,并且没有疼痛或其他创伤。控制微量元素的尺寸和形状,以控制进入皮肤的渗透深度。微量元素可以是“空心的”,使得通过其形成通道,以允许组合物从腔室流过微量元素并进入皮肤。备选地,微量元素可以是“固体”,并且在将微量元素施加到皮肤表面上以在角质层中形成开口之前或之后,将组合物直接施加到皮肤上。

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