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Methods of treating lupus based on antibody affinity and screening methods and compositions for use thereof
Methods of treating lupus based on antibody affinity and screening methods and compositions for use thereof
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机译:基于抗体亲和力治疗狼疮的方法及其筛选方法和组合物
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摘要
The invention provides methods identifying individuals suitable for treatment for lupus and methods of monitoring treatment, based on measuring antibody affinities, as well as of treating lupus based on measuring antibody affinities. The treatment entails administration of a conjugate comprising a non-immunogenic valency platform molecule and at least two double stranded DNA epitopes, such as DNA molecules, which bind to anti-DNA antibodies from the patient.
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