Composed of inclusion between B - cyclodextrin and praziquantel for treatment of schistosomiasis

摘要

"Composed of inclusion between 225 - clodextrina and praziquantel for treatment of schistosomiasis.New compound for the treatment of schistosomiasis, which increases the solubility of praziquantel to trade and, with it, the bioavailability of this anti paratsitu00e1rio,When administered via nasogastric mice Mus musculus, allowing a greater amount of the drug is available in the circulation, increasing its pharmacological effect.It also increases efficiency and reduces the number of worms alive after treatment via nasogastric, becoming an excellent option for the formulation of commercial PZQ available on the market.And also reduces the systemic toxicity of PZQ, due to the controlled release of the drug, which prevents the high plasma levels are achieved.