2- (3,5-Bis-trifluoromethyl-phenyl) -n- 6- (1,1-dioxo-1-yl -4,6-thiomorpholin-4-yl) -4- (4-fluoro-2) crystalline modification -methyl-phenyl) -pyridin-3-yl -n-methyl-isobutyramide

摘要

"2- (3,5-BIS-TRI-FLUORMETIL-FENIL) -N- ¢ 6- (1,1-DIOXO-1 LAMP ~ 6'-THOMORFOLIN-4-IL) -4- (4-" CRYSTALINE MODIFICATION Fluor-2-Methyl-Phenyl) -pyridin-3-yl! - N-Methyl-Isobutramide ". The present invention relates to a novel crystalline modification of 2- (3,5-bis-trifluoromethyl-phenyl) -N- ¢ 6- (1,1, -dioXo1 sym ¬ 6¬thiomorpholin-4-yl) -4- (4-Fluoro-2-methyl-phenyl) -pyridin-3-yl-N-methyl-isobutyram characterized by the following X-ray diffraction pattern obtained with a C ~ CU radiation at 20 ° C (2 theta) = 4.5, 6.4, 7.5, 7.7, 8.0, 8.2, 10.0, 10.2, 10.9, 11.1, 12.9, 13 , 14.0, 14.5, 15.1, 15.6, 16.2, 16.5, 17.3, 17.5, 18.0, 18.9, 19.3, 19.5 , 19.9, 20.1, 20.6, 21.0, 21.4, 22.7, 23.1 and 23.6 and an infrared spectrum with acute ranges at 2925, 2854, 1637, 1604, 1484 , 1395, 1375, 1285, 1230, 1172, 1125, 1082, 999, 943, 893, 863, 860, 782, 705, 684 cm -1 and wherein the extrapolated melting point (DSC) is 137.2.198. C.