首页> 外国专利> compound, drug, antigen presenting inhibitor, immunosuppressive agent, lymphocyte proliferation, and cell growth and maturation inhibitors, therapeutic or preventative agent, immune tolerance inducer, and anti-cancer drug

compound, drug, antigen presenting inhibitor, immunosuppressive agent, lymphocyte proliferation, and cell growth and maturation inhibitors, therapeutic or preventative agent, immune tolerance inducer, and anti-cancer drug

机译:化合物,药物,抗原呈递抑制剂,免疫抑制剂,淋巴细胞增殖以及细胞生长和成熟抑制剂,治疗或预防剂,免疫耐受诱导剂和抗癌药

摘要

"COMPOUND, MEDICINAL PRODUCT, ANTIGEN PRESENTATION INHIBITOR, IMMUNOSUPRESSOR AGENT, LYMPHOCYTE PROLIFERATION INHIBITORS, AND CELL GROWTH AND MATURATION, THERAPEUTIC OR PREVENTIVE AGENT, TOLERARY ANGOL, THERAPEUTIC ANTIGER, Unpublished ¢ 1,2,4! Triazolo ¢ 1,5-α! Pyrimidine derivative of the general formula (1): (1) prodrug thereof or a pharmaceutically acceptable salt thereof, which exhibits antigen presenting inhibitory activity and It is useful as a preventive and / or therapeutic agent for immune rejection and / or graft versus host transplantation reaction in organ / bone marrow transplantation, autoimmune disease, allergic disease and / or inflammatory disease and also useful as an anti-cancer drug or as a an immune tolerance inducer for transplanted organ / transplanted bone marrow.
机译:“化合物,药物,抗原呈递抑制剂,免疫抑制剂,淋巴细胞增殖抑制剂,细胞生长和成熟,治疗或预防剂,耐受性Angol,治疗性抗癌剂,Tri,¢1,¢1,¢1,¢1,¢1,¢1,¢1,¢1,¢1,¢1,¢1,¢1,o!¢1,¢!,¢1,¢!,¢!, 1,1,1,1,1!,1 !!通式(1)的嘧啶衍生物:(1)其前药或其药学上可接受的盐,其显示抗原呈递抑制活性,并且可用作免疫排斥和/或移植物抗宿主移植的预防和/或治疗剂在器官/骨髓移植,自身免疫性疾病,变应性疾病和/或炎症性疾病中起反应,并且还可用作抗癌药或移植器官/移植骨髓的免疫耐受诱导剂。

著录项

  • 公开/公告号BRPI0410867A

    专利类型

  • 公开/公告日2006-07-04

    原文格式PDF

  • 申请/专利权人 NIPPON KAYAKU KABUSHIKI KAISHA;

    申请/专利号BR2004PI10867

  • 申请日2004-06-02

  • 分类号C07D487/04;A61K31/519;A61K31/5377;A61P1/00;A61P1/04;A61P3/10;A61P7/04;A61P7/06;A61P11/06;A61P13/12;A61P17/00;A61P21/04;A61P25/00;A61P29/00;A61P35/00;A61P37/06;A61P37/08;A61P43/00;

  • 国家 BR

  • 入库时间 2022-08-21 21:40:03

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