Methods for forming a disulphide bond and to modify chemically a proteu00ecna, a peptu00ecdeo or an amino acid compound, method for preparing the compound, using the compound, and proteu00ecna,Peptu00ecdeo or amino acid

摘要

Methods to form a disulphide bond and to modify chemically a proteu00ecna, a peptu00ecdeo or an amino acid compound, method for preparing the compound, using the compound, and proteu00ecna,Peptu00ecdeo or amino acid. Methods and reagents for the formation of disulfide bonds, particularly in proteins, peptides and amino acids.Methods and reagents are particularly useful for the controlled glycosylation of proteins, peptides and amino acids.The methods use compounds of tiossulfonato or selenonil - sulfide as reagents or intermediates.Some proteins and some peptides comprising groups of selenonil - sulfide also form part of the invention.