首页> 外国专利> PHARMACEUTICAL COMPOSITION CONTAINING ANTAGONIST LTB4 AND COX2 INHIBITOR OR COMBINED COX1 / COX2 INHIBITOR

PHARMACEUTICAL COMPOSITION CONTAINING ANTAGONIST LTB4 AND COX2 INHIBITOR OR COMBINED COX1 / COX2 INHIBITOR

机译:包含拮抗剂LTB4和COX2抑制剂或组合的COX1 / COX2抑制剂的药物组合物

摘要

The application describes a pharmaceutical composition comprising an LTB antagonist that carries a hydroxy and benzamidine group, or a tautomer thereof, a pharmaceutically acceptable salt or solvate, in particular a compound of formula (I), in which R and A have the meanings indicated in the claims, or its tautomer, pharmaceutically acceptable salt or solvate (1) and at least one cyclooxygenase-2 inhibitor, a combined cox1 / cox2 inhibitor or its pharmaceutically acceptable salt or solvate (), and a pharmaceutically acceptable carrier or excipient and not necessarily one or more other therapeutic ingredients. The international application was published along with an international search report.
机译:本申请描述了一种药物组合物,其包含带有羟基和苄group基的LTB拮抗剂或其互变异构体,药学上可接受的盐或溶剂化物,特别是式(I)的化合物,其中R和A具有在下文中所示的含义。权利要求或其互变异构体,药学上可接受的盐或溶剂化物(1)和至少一种环氧合酶2抑制剂,cox1 / cox2组合抑制剂或其药学上可接受的盐或溶剂化物()和药学上可接受的载体或赋形剂,不一定一种或多种其他治疗成分。国际申请与国际检索报告一同发布。

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