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POXVIRUS CONTAINING FORMULATIONS AND PROCESS FOR PREPARING STABLE, POXVIRUS CONTAINING FORMULATIONS
POXVIRUS CONTAINING FORMULATIONS AND PROCESS FOR PREPARING STABLE, POXVIRUS CONTAINING FORMULATIONS
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机译:含痘苗病毒的配方及制备稳定的含痘苗病毒的配方的方法
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摘要
: The present invention relates to a formulation, in particular an aqueous formulation comprising (i) a poxvirus of one of the genera orthopoxvirus, avipoxvirus, parapoxvirus, capripoxvirus and suipoxvirus, (ii) a disaccharide, (iii) a pharmaceutically acceptable polymer and optionally (iv) a buffer. The aqueous formulation is particularly suitable for freeze drying processes resulting in a stable, freeze-dried, poxvirus containing composition. The invention further concerns a method for preparing a freeze-dried, poxvirus containing composition and the thus obtained product.
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