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3-(4-aminophenyl) thienopyrimid-4-one derivatives as MCH R1 antagonists for the treatment of obesity, diabetes, depression and anxiety

机译:3-(4-氨基苯基)噻吩并嘧啶-4-酮衍生物作为MCH R1拮抗剂,用于治疗肥胖,糖尿病,抑郁症和焦虑症

摘要

This invention relates to novel arylamines which are antagonists of the melanin-concentrating hormone receptor 1 (MCH R1), to pharmaceutical compositions containing them, to processes for their preparation, and to their use in medicines for the treatment of obesity, diabetes, depression, and/or anxiety. Compounds of the invention have the formula.
机译:本发明涉及新颖的芳胺,其是黑色素浓缩激素受体1(MCH R1)的拮抗剂,涉及含有它们的药物组合物,其制备方法,以及它们在治疗肥胖,糖尿病,抑郁症,和/或焦虑。本发明的化合物具有下式。

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