首页> 外国专利> An isolated Apo-2 ligand variant polypeptide comprising an amino acid sequence which differs from the native sequence Apo-2 ligand

An isolated Apo-2 ligand variant polypeptide comprising an amino acid sequence which differs from the native sequence Apo-2 ligand

机译:分离的Apo-2配体变体多肽,其包含与天然序列Apo-2配体不同的氨基酸序列

摘要

An isolated Apo-2 ligand variant polypeptide comprising an amino acid sequence which differs from the native Apo-2 sequence and has a specific amino acid substitution at the residue positions in SEQ ID NO:1 (Figure 1). Also disclosed is an isolated nucleic acid comprising the nucleotide sequence encoding the Apo-2 ligand variant, a vector comprising the nucleic acid and a host cell comprising the vector.
机译:分离的Apo-2配体变体多肽,其包含与天然Apo-2序列不同的氨基酸序列,并且在SEQ ID NO:1的残基位置具有特定的氨基酸取代(图1)。还公开了包含编码Apo-2配体变体的核苷酸序列的分离的核酸,包含所述核酸的载体和包含所述载体的宿主细胞。

著录项

  • 公开/公告号NZ537920A

    专利类型

  • 公开/公告日2006-10-27

    原文格式PDF

  • 申请/专利权人 GENENTECH INC;

    申请/专利号NZ20000537920

  • 发明设计人 ASHKENAZI AVI J;

    申请日2000-06-26

  • 分类号C12N5/10;C12N15/19;C12N1/21;A61K47/02;A61K38/19;C07K14/705;

  • 国家 NZ

  • 入库时间 2022-08-21 21:38:02

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