Compounds 1, 2, 3, 4, 5, 6. Hksahydrw - 2, 6 - 3 - 1,2,3,4 (10) Bnzazwsynwl Mythanw 5, 6-Hexahydro - 10 - 3 - 2,6 - Methano Benzazocin. OLS

摘要

Abstract: the present invention relates to compounds according to general formula (I X represents a single bond O, single bond, C1-C4-alkylene, or bridge Alkylyn alkylene bridge from the atom to the carbon may be carbon M Tfra branched or not from the unbranched may contain one or two atoms of Akhtyaryaly atom oxygen oxygen anywhere on the bridge. R1 is methy, hydrogen ethyl or phenyl R2 is hydrogen or methyl, R3 is hydrogen, fluorinemEthyl, hydroxyl, bromine, chlorine, or methoxy, R4 is methyl, hydrogen, or ethyl, R5 is methyl, hydrogen, or ethyl R6 is methyl, hydrogen, or ethyl, R7 is cyclohexyl, tert-butyl phenyl carries Akhtarya alternatives R9 and R10 and t That is the same or different, and is hydrogen; R8 or CC4-alkyle; Z is oxygen; NH; or sulfur; R9 is methyl, hydrogen, chlorine, fluorine, bromine, or methoxy, R10 an hydrogen, parallel, chlorine, fluorine, methyl bromine, or methoxy, optionally in the form of light Zmra optical 15.