INHIBITORS OF AMINOTRANSPHERASE DEPENDENT ON AMINO ACIDS OF RAMIFIED CHAIN AND ITS USE IN THE TREATMENT OF DIABETIC RETINOPATHY.

摘要

A compound of Formula IV in which R1-R4 is hydrogen or alkyl; X is NR5 or O; R5 is hydrogen or alkyl; R6 is alkyl, benzyl, alkoxyalkanoyl, arylalkyl, alkoxy, cycloalkyl, allyl, alkylcycloalkyl, haloalkyl trisubstituted, and in which R1-R4 are each hydrogen, then R6 is not hydrogen or methyl; or one of its pharmaceutically acceptable salts, esters, prodrugs, or amides.