ASSESSMENT OF VITAMIN D RECEPTORS ALLELIC VARIATION

摘要

The present invention provides a genetic test for assaying predisposition toand/or resistance to high rates of bone turn-over,development of low bone mass and responsiveness or otherwise to therapeuticmodalities. This is a specific model for use inprediction of osteoporosis and likely response to preventive or therapeuticmodalities. It is a general model of allelic variation intranscriptional regulators determining physiological set-points and thussusceptibility or resistance to certain pathophysiologicalstates.