首页> 外国专利> REGULATION OF GENE EXPRESSION USING CHROMATIN REMODELLING FACTORS

REGULATION OF GENE EXPRESSION USING CHROMATIN REMODELLING FACTORS

机译:利用染色质重塑因子调控基因表达

摘要

The invention provides a method to regulate expression of a gene of interestina plant comprising, introducing into the plant a first nucleotide sequencecomprising,the gene of interest operatively linked to a first regulatory region, and anoperatorsequence capable of binding a fusion protein, and a second nucleotide sequencecomprising a second regulatory region in operative association with anucleotidesequence encoding the fusion protein. The fusion protein comprising, a DNAbindingprotein, or a portion thereof, capable of binding the operator sequence, and arecruitment factor protein, or a portion thereof, capable of binding achromatinremodelling protein. In this manner, expression of the second nucleotidesequenceproduces the fusion protein that regulates expression of the gene of interest.
机译:本发明提供了一种调节目的基因表达的方法在植物,其包括将第一核苷酸序列引入植物中包括,感兴趣的基因可操作地连接到第一个调控区域,并且算子能够结合融合蛋白的序列和第二个核苷酸序列包括与第二受体区域可操作结合的第二调节区。核苷酸编码融合蛋白的序列。包含DNA的融合蛋白捆绑能够结合操纵子序列的蛋白质或其一部分,以及募集因子蛋白或其部分,能够结合染色质重塑蛋白质。以这种方式,第二核苷酸的表达顺序产生调节目的基因表达的融合蛋白。

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