The present invention relates to a method of marking and purifying the nucleic acid of interest in a biological sample to be treated, consisting in: • have a single reaction vessel, to introduce into the receptacle of the reaction: - the biological sample, - at least a reagent of the marking of nucleic acids, - at least one solid support for the adsorption of said nucleic acids, - any ingredient necessary for the marking of the nucleic acids and / or to the immobilization of said nucleic acids on the support, • place the contents of container, and isolate the nucleic acids thus marqués.l' invention finds a preferred application in the diagnosis.
展开▼