PREPARATION OF RED BLOOD CELLS WITH A MODIFIED LEVEL OF BLOOD GROUP ANTIGEN EXPRESSION AND THEIR USE IN THE QUALITY CONTROL OF BLOOD TYPING REAGENTS

摘要

A kind of horizontal sugar-modified enzyme for reducing blood group antigens and using at least one immundominance preparing red blood cell expression, such as alpha-N-acetylgalactosaminidase or alpha-galactosidase. The level that red blood cell preferably generates antigen presentation is substantially equal to the antigen of clinically significant threshold value. Red blood cell it is manufactured according to the method for quality control blood typing reagent and calibration with provide accurately determine test macro and standardized blood group type.