METHOD FOR SURFACE MODIFICATION BY COATING WITH HIGHLY POROUS CALCIUM PHOSPHATE THIN FILM

摘要

The present invention relates to a surface modification method by forming a porous calcium phosphate thin film, specifically 1) preparing a calcium ion solution and a phosphate ion solution; 2) mixing the calcium ion solution and the phosphate ion solution to prepare a mixed ion solution in which the ion concentrations of calcium and phosphoric acid are 1 to 3 mM and 3 to 5 mM, respectively; And 3) forming a porous calcium phosphate thin film on a solid surface by using the mixed ion solution. The method of the present invention forms a porous surface structure having a low crystalline three-dimensional conformation on a solid surface, thereby providing excellent biocompatibility, cell compatibility, and osteoconductivity in the surface of an implantable implant or medical implant. It can be usefully used to modify to have).