Preparing temozolomide base, useful as antitumor agent, comprises preparing temozolomide hydrochloride and converting to temozolomide base in acidic medium

摘要

Preparing temozolomide base comprises preparing temozolomide hydrochloride and converting the temozolomide hydrochloride to temozolomide base in acidic medium by contacting temozolomide hydrochloride with an organic acid. An independent claim is also included for the preparation of temozolomide hydrochloride ACTIVITY : Cytostatic. No biological data given. MECHANISM OF ACTION : None given.