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Use Of Genetic Polymorphisms To Predict Drug-Induced Hepatotoxicity
Use Of Genetic Polymorphisms To Predict Drug-Induced Hepatotoxicity
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机译:利用遗传多态性预测药物诱发的肝毒性
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摘要
IL1A or a gene located near IL1A on chromosome 2q14 may contribute to hepatotoxicity, as measured by increased serum levels of aspartate transaminase, during N-benzoyl-staurosporine treatment for macular edema. Accordingly, genetic polymorphisms in the IL1A gene are useful as biomarkers for predicting staurosporine derivative-mediated hepatotoxicity.
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