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Ultrasensitive detection of prions by automated protein misfolding cyclic amplification
Ultrasensitive detection of prions by automated protein misfolding cyclic amplification
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机译:通过自动蛋白质错误折叠循环扩增超灵敏地检测of病毒
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摘要
A highly sensitive method is provided for the detection of prions in a sample. These methods may be used to diagnose prion mediated transmissible spongiform encephalopathies such as bovine spongiform encephalopathy, Creutzfeldt-Jakob disease, scrapie, or chronic wasting disease. In particular a method for serial automated cyclic amplification of prion is disclosed. The method is both rapid and highly sensitive making it ideal for high throughput testing.
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