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Use of tempol for the treatment of Li-Fraumeni syndrome and ataxia telangiectasia
Use of tempol for the treatment of Li-Fraumeni syndrome and ataxia telangiectasia
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机译:tempol在治疗Li-Fraumeni综合征和共济失调毛细血管扩张中的用途
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摘要
The present invention provides a method for the prophylactic and therapeutic treatment of cancer. The method comprises administering to an animal, preferably a mammal, more preferably a human, at risk for developing a cancer or having a cancer a nitroxide or a prodrug thereof, wherein the nitroxide or prodrug thereof preferably is alicyclic or heterocyclic and more preferably is a compound of Formula (I) or Formula (II): in an amount sufficient to prevent or treat said cancer, wherein said cancer is susceptible to prevention or treatment by said nitroxide or prodrug thereof. Also provided is a composition for use in the method; 展开▼