Long-acting glucagon-like peptide-1 analogs

摘要

PEPTIDE-1 ANALOGUE LIKE GLUCAGON WITH LONG DURATION OF ACTION. Novel glp-1 analogs having improved biological potency as well as extended pharmacological activity are described herein. More specifically, the present invention relates to glp-1 analogs (28 or 29 aa in length) comprising amino acids at one or more of the following positions: 8, 20, 27, 30 and 33.