Process for preparing trityl irbesartan and use thereof in irbesartan synthesis process

摘要

method of production of 2 - butyl - 4 - spirocyklopentan - 1 - [(2 '- (1 - trifenylmethyl - tetrazole - 5 - yl) diphenyl - 4 - yl) methyl 2 - imidazolin - 5 - the (tritylirbesartanu)in nemzse 2 - butyl - 4 - spirocyklopentan - 2 - imidazolin - 5 - he formula iii will react with 4 - brommethly - 2 '- (1 - trifenylmethyltetrazol - 5 - yl) bifenylem formula vi in aproticku00e9m rozpoustedle in the presence of uhlicitawell crown ether alkali metal for catalyser for formation of tritylirbesartanu formula, which is obtained after filtration the salt of matecnu00e9ho lye zahustenu00edm and cooling.tritylirbesartan is a move to irbesartan.