首页>
外国专利>
METABOLITES OF SELECTIVE MODULATORS OF ANDROGEN RECEPTORS AND METHODS OF THEIR APPLICATION
METABOLITES OF SELECTIVE MODULATORS OF ANDROGEN RECEPTORS AND METHODS OF THEIR APPLICATION
展开▼
机译:雄激素受体选择性调节剂的代谢物及其应用方法
展开▼
页面导航
摘要
著录项
相似文献
摘要
The present invention relates to metabolites of the class of substances directed to the androgen receptor (ARTA). SARM compounds and their metabolites, either on their own or in the form of a composition, can be used for a) male contraception; b) treating a range of hormonal disorders, such as those associated with age-related decline in male androgen levels in men (ADAM), such as fatigue, depression, decreased libido, sexual dysfunction, erectile dysfunction, hypogonadism, osteoporosis, hair loss, anemia, obesity, sarcopenia osteopenia, benign prostatic hyperplasia, mood and cognitive changes, and prostate cancer; c) treating disorders related to lowering androgen levels in women (ADIF), such as sexual dysfunction, decreased sexual libido, hypogonadism, sarcopenia, osteopenia, osteoporosis, mood and cognitive changes, depression, anemia, hair loss, obesity, endometriosis, breast cancer, uterine cancer and ovarian cancer; d) treatment and / or prevention of acute and / or chronic muscle hypotrophy; e) prevention and / or treatment of dry eyes; f) oral androgen replacement therapy; g) reducing, terminating, or regressing prostate cancer; and / or h) inducing apoptosis in cancer cells.
展开▼