Improved vaccine for immunization against Flavivirus infections

摘要

Vaccine for immunisation against tick-borne encephalitis (TBE) virus comprises non-infectious, sub-viral particles that consist essentially of the E protein (I) in its complete, native form and opt. the prM/M protein (II), both proteins being derived from TBE virus. Also new are: (1) vaccines for immunisation against flavivirus (esp. TBE virus) contg. nucleic acid (III) that encodes (I) and (II) in at least essentially complete, native form and (2) vectors contg. (III), other than plasmid vectors derived from SV40. IMAGE